九强新闻
CKMB vs CKMB mass
Published：2020-05-27
Source：[英文]九强生物
CK-MB has been the first choice marker for the diagnosis of myocardial infarction before cTn appeared. After acute myocardial infarction, CK-MB began to increase at 3 hours, peaked at 12 hours, and returned to baseline levels within 48-72 hours.
Compared with 7-14 days of cTn, the time for CK-MB to return to baseline is shorter, which also makes it play an important role in the diagnosis of early reinfarction and make up for the lack of cTn.
The clinical measurement of CK-MB mainly includes immunoassay activity measurement and quality measurement.
Because there are many factors that interfere with activity measurement, false positives are prone to occur. In particular, the phenomenon of CK-MB>CK sometimes appears, which causes confusion to clinical judgment.
Immunosuppression method: has certain limitations
CKMB mass
CKMB mass
Advantages of quality determination
The biochemical platform recommends the use of BSBE CKMB mass
BSBE CKMBmass test kit
When the CK/CKMB inversion occurs in our daily work or the pseudo-increasing CKMB is suspected, we should actively communicate with the clinic to explain it and recommend CKMB quality measurement (CKMB/mass).
BSBE latex immunoturbidimetric method CKMBmass uses monoclonal antibody to directly recognize CKMB, which can eliminate many interference factors, fundamentally solve the occurrence of CKMB greater than CK inversion, and break through the limitations of traditional immunosuppressive activity measurement to ensure clinical determination The accuracy of the results greatly reduces the testing cost, which is beneficial to the development of various laboratories.
GCELL CKMBmass kit Performance
1.The first biochemical platform in China for the rapid determination of CK-MB (MASS)
2.Good correlation with Roche chemiluminescence (R2=0.99)
3.Detection enzyme quality, strong anti - interference, good stability
4.Applicable to all automatic biochemical analyzer, batch detection, fast speed, effective cost saving
CKMBmass Keywords
Solved the problem that ckmb is greater than ck and the result is inverted. Specimens where inversion problems often occur:
1.Cancer patient specimen
2. Children's specimens
3. Giant ckemia specimen
The advantages are as follows:
A.Measuring blood concentration by mass method: unit ng/ml
B.The same as the principle of luminescence: the detection results of monoclonal antibodies
C.Biochemical platform: fast speed and cost saving
D.Solve the shortcomings of immunosuppression method, higher specificity and higher sensitivity