Fibrin Degradation Products
Method: Latex Enhanced IT Liquid reagent, R1: R2=3:1
CLINICAL SIGNIFICANCE
Fibrin degradation products reflects the fibrinolysis function. The level increases obviously in the following disease:
a.Primary fibrinolysis hyperfunction
b.Secondary fibrinolysis hyoerfunction:kidney disease, organ transplantation rejection,thrombolytic therapy etc.
c.Vascular embolism disease: pulmonary embolism, myocardial infaraction, deep venous thrombosis.
d.Leukemia chemotherapy after the induction period, Hemorrhagic disease of grow in quantity of platelets,uremia,liver disease etc.
PRECISION
|
Intra assay precision |
||
|
N=20 |
level 1 |
level 2 |
|
Mean(IU/ml) |
6.93 |
12.40 |
|
SD |
0.32 |
0.42 |
|
CV(%) |
4.62 |
3.39 |
|
Inter assay precision |
|||
|
N=5 |
Batch 1 |
Batch 2 |
Batch 3 |
|
Mean(IU/ml) |
12.31 |
11.94 |
12.54 |
|
|
12.26 |
||
|
(Xmax-Xmin)/ |
(12.54-11.94)/12.26*100=4.89% |
||
Interference
|
Analytes |
Concentration |
|
Bilirubin |
20 mg/dl |
|
Hemoglobin |
500 mg/dl |
|
Intralipid |
600 mg/dl |
Linearity
Linearity is 2.5~ 80 μg/mL.